Observation : Since more 15 years Mrs N. VER was followed for a primary sleep hypersomnia. Her first complaint in 2003 is daytime somnolence (Epworth Score of 20) Clinical investigations with PSG and MSLT were performed in 2003, 2004, 2010, 2014 and 02-2018. Mean latency was higher than 8min in 2003, 2004 and 2018 but lower in 2010, 2014. HLA phenotype is DR11/DR13 DQ03/03. PSG show on all polysomnography a sleep fragmentation (30 arousal), a reduction of rem sleep duration (8-10% of TST). (…)
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